Generic entry timeline

Mucinex generics — when can they launch?

Mucinex (guaifenesin) · Generic (multiple manufacturers) · 3 active US patents · 0 expired

Earliest patent expiry
2035-11-13
9 years remaining
Full patent estate to
2035-11-13
complete protection through 2035
FDA approval
1952-01-01
Generic (multiple manufacturers)

Where Mucinex sits in the generic timeline

Long-dated protection: earliest active US patent for Mucinex extends to 2035 (~9 years out). Generic competition is at least 4 years away. Lifecycle moves (new formulations, label extensions, combination filings) typically execute 18-36 months ahead of cliff.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Method of Use — 3 patents

FDA U-codes carved out by Mucinex patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-2023(no description)

Sample patent estate

Showing 3 of 3 active US patents. View full estate on the Mucinex drug page →

  • US10105324 Method of Use · expires 2035-11-13
    This patent protects a method of treating or ameliorating a condition with an immediate release oral guaifenesin solution that includes propylene glycol and glycerol as solvents.
    USPTO title: Immediate release oral guaifenesin solution
  • US9549907 Method of Use · expires 2035-11-13
    This patent protects an immediate release oral solution for guaifenesin that includes propylene glycol and glycerol as solvents to increase guaifenesin bioavailability.
    USPTO title: Immediate release oral guaifenesin solution
  • US9808431 Method of Use · expires 2035-11-13
    This patent protects an immediate release oral solution for guaifenesin that includes propylene glycol and glycerol as solvents to increase guaifenesin bioavailability.
    USPTO title: Immediate release oral guaifenesin solution

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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