Generic entry timeline

AZELASTINE HYDROCHLORIDE generics — when can they launch?

AZELASTINE HYDROCHLORIDE (AZELASTINE HYDROCHLORIDE) · · 5 active US patents · 1 expired

Earliest patent expiry
2026-08-24
expired
Full patent estate to
2028-06-04
complete protection through 2028
FDA approval
1996

Where AZELASTINE HYDROCHLORIDE sits in the generic timeline

All listed Orange Book patents for AZELASTINE HYDROCHLORIDE have expired. Generic entry is permitted, and ANDA filers can launch without patent infringement risk. Hatch-Waxman exclusivity (NCE/ODE/PED) may still apply if recently approved.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Formulation — 4 patents
  • Other — 1 patent

Sample patent estate

Showing 5 of 5 active US patents. View full estate on the AZELASTINE HYDROCHLORIDE drug page →

  • US8168620 Other · expires 2026-08-24
    This patent protects a pharmaceutical product that combines azelastine or a derivative with a steroid, suitable for nasal or ocular administration.
    USPTO title: Combination of azelastine and steroids
  • US8071073 Formulation · expires 2028-06-04
    This patent protects pharmaceutical compositions containing azelastine hydrochloride, including optional additional active agents and carriers to reduce post-nasal drip and bitter taste.
    USPTO title: Compositions comprising azelastine and methods of use thereof
  • US8071073 Formulation · expires 2028-06-04
    This patent protects pharmaceutical compositions containing azelastine hydrochloride, including optional additional active agents and carriers to reduce post-nasal drip and bitter taste.
    USPTO title: Compositions comprising azelastine and methods of use thereof
  • US8071073 Formulation · expires 2028-06-04
    This patent protects pharmaceutical compositions containing azelastine hydrochloride, including optional additional active agents and carriers to reduce post-nasal drip and bitter taste.
    USPTO title: Compositions comprising azelastine and methods of use thereof
  • US8071073 Formulation · expires 2028-06-04
    This patent protects pharmaceutical compositions containing azelastine hydrochloride, including optional additional active agents and carriers to reduce post-nasal drip and bitter taste.
    USPTO title: Compositions comprising azelastine and methods of use thereof

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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