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ZIPRASIDONE HYDROCHLORIDE
ZIPRASIDONE HYDROCHLORIDE is a drug. It is currently FDA-approved (first approved 2001).
Ziprasidone hydrochloride is an antipsychotic medication used to treat conditions such as Major Depressive Disorder, Schizophrenia, Mania, Delusional Disorder, and Acute Exacerbation of Psychosis. It is a serotonin-dopamine antagonist, which means it works by blocking the action of serotonin and dopamine in the brain, according to ChEMBL.
At a glance
| Generic name | ZIPRASIDONE HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 2001 |
Approved indications
Boxed warnings
- WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis [see Warnings and Precautions (5.1) ] . WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS See full prescribing information for complete boxed warning. Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis ( 5.1 )
Common side effects
Key clinical trials
- An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine (PHASE4)
- Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes (PHASE3)
- Maternal And Infant Antipsychotic Study
- A Study to Assess Stroke Risk Among Users of Typical Versus Atypical Antipsychotics Stratified by Broad Age Group
- Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia (PHASE1)
- Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD) (PHASE4)
- Impact of Aripiprazole Once Monthly Medications on Changes in Brain Structure and Metabolism (PHASE4)
- Efficacy and Safety of Iloperidone Compared With Placebo and Active Control in Subjects With Acute Schizophrenia (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ZIPRASIDONE HYDROCHLORIDE CI brief — competitive landscape report
- ZIPRASIDONE HYDROCHLORIDE updates RSS · CI watch RSS
Frequently asked questions about ZIPRASIDONE HYDROCHLORIDE
What is ZIPRASIDONE HYDROCHLORIDE?
When was ZIPRASIDONE HYDROCHLORIDE approved?
What development phase is ZIPRASIDONE HYDROCHLORIDE in?
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing