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Zinc Supplementation
Zinc acts as a cofactor for numerous enzymes and proteins involved in immune function, protein synthesis, wound healing, and antioxidant defense.
Zinc acts as a cofactor for numerous enzymes and proteins involved in immune function, protein synthesis, wound healing, and antioxidant defense. Used for Zinc deficiency prevention and treatment, Immune support and common cold duration reduction, Wound healing and tissue repair.
At a glance
| Generic name | Zinc Supplementation |
|---|---|
| Also known as | Supplementation, Zinc Acetate |
| Sponsor | University of Douala |
| Drug class | Mineral supplement / Essential trace element |
| Modality | Small molecule |
| Therapeutic area | Nutritional supplementation / Immunology / General health |
| Phase | FDA-approved |
Mechanism of action
Zinc is an essential trace element required for the function of over 300 enzymes and plays critical roles in immune cell development and activation, DNA synthesis, and cellular signaling. It supports both innate and adaptive immunity, promotes wound healing through collagen synthesis, and protects cells from oxidative stress through metallothionein and superoxide dismutase activity.
Approved indications
- Zinc deficiency prevention and treatment
- Immune support and common cold duration reduction
- Wound healing and tissue repair
- Age-related macular degeneration (as part of AREDS formulation)
Common side effects
- Nausea
- Copper deficiency (with chronic high-dose supplementation)
- Gastrointestinal upset
- Metallic taste
Key clinical trials
- Single Strain Probiotic (NA)
- Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome. (NA)
- Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial (PHASE2)
- Zinc Supplementation With Botulinum Toxin for Overactive Bladder (PHASE2)
- Zinc Supplementation and Infections in Older Medical Patients (NA)
- Effectiveness of Pulsed Electromagnetic Fields and Nutraceutical Supplementation in Women With Distal Radius Fracture (NA)
- Nutritional Supplement for Treating Chemotherapy Induced Neuropathy (PHASE4)
- Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Zinc Supplementation CI brief — competitive landscape report
- Zinc Supplementation updates RSS · CI watch RSS
- University of Douala portfolio CI