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ZENTEL and Vitamin A Soft Capsules
ZENTEL (albendazole) is an anthelmintic that inhibits microtubule polymerization in parasitic worms, while Vitamin A supports immune function and mucosal health.
ZENTEL (albendazole) is an anthelmintic that inhibits microtubule polymerization in parasitic worms, while Vitamin A supports immune function and mucosal health. Used for Intestinal nematode infections (roundworm, hookworm, whipworm), Cestode infections (tapeworm), Vitamin A deficiency in endemic parasitic regions.
At a glance
| Generic name | ZENTEL and Vitamin A Soft Capsules |
|---|---|
| Also known as | albendazole and vitamin A |
| Sponsor | Chengdu Maternal and Children's Health Care Hospital |
| Drug class | Anthelmintic + Vitamin supplement |
| Target | β-tubulin (albendazole component) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease / Parasitology |
| Phase | FDA-approved |
Mechanism of action
Albendazole binds to β-tubulin in parasitic nematodes and cestodes, disrupting microtubule formation and causing paralysis and death of the worms. The combination with Vitamin A addresses nutritional deficiencies common in populations with parasitic infections, as Vitamin A is essential for immune response and epithelial integrity. This fixed-dose combination is commonly used in maternal and child health programs in endemic regions.
Approved indications
- Intestinal nematode infections (roundworm, hookworm, whipworm)
- Cestode infections (tapeworm)
- Vitamin A deficiency in endemic parasitic regions
Common side effects
- Abdominal pain
- Diarrhea
- Nausea
- Headache
- Dizziness
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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