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Xylitol Gum
Xylitol gum works by stimulating saliva production, which helps to neutralize acids and remineralize teeth.
Xylitol gum works by stimulating saliva production, which helps to neutralize acids and remineralize teeth. Used for Prevention of tooth decay and gum disease.
At a glance
| Generic name | Xylitol Gum |
|---|---|
| Sponsor | West Virginia University |
| Drug class | Sugar substitute |
| Modality | Small molecule |
| Therapeutic area | Dental health |
| Phase | Phase 3 |
Mechanism of action
The increased saliva flow helps to wash away bacteria and food particles, reducing the risk of tooth decay and gum disease. This is achieved through the activation of salivary glands, which produce more saliva in response to the xylitol stimulus.
Approved indications
- Prevention of tooth decay and gum disease
Common side effects
- Diarrhea
- Nausea
- Abdominal cramps
Key clinical trials
- The Effect of Chewing Gum on Nausea, Vomiting and Bowel Function After Colorectal Surgery (NA)
- Microbiome Alterations With Xylitol (MAX) in Pregnancy (PHASE1, PHASE2)
- Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia (PHASE3)
- Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial (PHASE2, PHASE3)
- Effect of Different Products to Support Plaque Control During Daytime (NA)
- Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy (NA)
- Effects of Music Application and Gum Chewing on Pain, Anxiety, and Patient Satisfaction During Episiotomy Repair (NA)
- Effects of Caffeine and Nicotine Gum on Balance Performance in Athletes (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |