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Xe 133 (xenon (133Xe) gas)
Xe 133 (generic name: xenon (133Xe) gas) is a Inhalation Diagnostic Agent [EPC] drug developed by Mallinckrodt. It is currently FDA-approved for Pulmonary Function Evaluation, Lung Imaging, Cerebral Blood Flow Assessment.
Xenon-133 gas (Xe 133), marketed by Mallinckrodt, is a diagnostic agent used primarily for pulmonary function evaluation, holding a niche but established position in the market since its approval. Its key strength lies in its unique mechanism of action, allowing precise detection in the lungs, which provides valuable diagnostic insights for respiratory conditions. The primary risk is the expiration of the key composition patent in 2028, which could lead to increased competition from generic alternatives, including xenon (127Xe) gas, already approved since 1982.
At a glance
| Generic name | xenon (133Xe) gas |
|---|---|
| Sponsor | Mallinckrodt |
| Drug class | Inhalation Diagnostic Agent [EPC] |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Approved indications
- Pulmonary Function Evaluation
- Lung Imaging
- Cerebral Blood Flow Assessment
Common side effects
- Adverse reactions
- Nausea
Key clinical trials
- Comparison of 133Xe Scintigraphy With 19F MRI for Evaluation of Lung Ventilation Function: A Non-Inferiority Comparison (DIAL1001007) (EARLY/Phase 1)
- Evaluation of Hyperpolarized 129Xe MRI as Compared to 133Xe Scintigraphy for the Assessment of Pulmonary Function in Patients Being Evaluated for Possible Lung Resection Surgery (Phase 3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Xe 133 CI brief — competitive landscape report
- Xe 133 updates RSS · CI watch RSS
- Mallinckrodt portfolio CI
Frequently asked questions about Xe 133
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Related
- Drug class: All Inhalation Diagnostic Agent [EPC] drugs
- Manufacturer: Mallinckrodt — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Pulmonary Function Evaluation
- Indication: Drugs for Lung Imaging
- Indication: Drugs for Cerebral Blood Flow Assessment
- Compare: Xe 133 vs similar drugs
- Pricing: Xe 133 cost, discount & access