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wound infiltration
Wound infiltration is a local anesthetic technique that delivers anesthetic agents directly into wound tissues to provide pain relief during and after surgical procedures.
Wound infiltration is a local anesthetic technique that delivers anesthetic agents directly into wound tissues to provide pain relief during and after surgical procedures. Used for Local anesthesia for wound closure and minor surgical procedures.
At a glance
| Generic name | wound infiltration |
|---|---|
| Also known as | Wound |
| Sponsor | Seoul National University Bundang Hospital |
| Modality | Small molecule |
| Therapeutic area | Surgery/Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Wound infiltration involves injecting local anesthetic solutions (typically lidocaine or similar agents) directly into the surgical wound and surrounding tissues. This blocks nerve conduction in the infiltrated area, providing localized anesthesia and analgesia. The technique is commonly used in minor surgical procedures and wound closure to minimize patient discomfort.
Approved indications
- Local anesthesia for wound closure and minor surgical procedures
Common side effects
- Local tissue irritation
- Allergic reaction (rare, agent-dependent)
- Systemic toxicity from anesthetic agent (if excessive dose)
Key clinical trials
- A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China. (PHASE3)
- Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial (NA)
- Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery (NA)
- Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults (PHASE4)
- Postoperative Analgesia and Ventilation After Cardiac Surgery
- ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
- Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty. (NA)
- Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |