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water-soluble therapy
water-soluble therapy is a Small molecule drug developed by University of Virginia. It is currently FDA-approved.
Water-soluble therapy refers to a formulation approach that enhances the bioavailability and solubility of pharmaceutical compounds in aqueous environments.
Water-soluble therapy, also known as water therapy, has been studied in various conditions including dentin sensitivity, knee osteoarthritis, overweight and obesity, cognitive change, and psychophysiologic reaction. The therapy involves the use of small molecule compounds, such as potassium nitrate and sodium fluoride, which are administered in a water-based solution, often in conjunction with other treatments like low-level laser therapy.
At a glance
| Generic name | water-soluble therapy |
|---|---|
| Sponsor | University of Virginia |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
This is a formulation technology rather than a specific drug mechanism. Water-soluble therapies improve drug dissolution and absorption by modifying the physical or chemical properties of active pharmaceutical ingredients to increase their aqueous solubility. This approach is commonly applied across multiple drug classes to enhance therapeutic efficacy and reduce variability in drug delivery.
Approved indications
Common side effects
Key clinical trials
- Mobilization and Outcomes After Venous Closure
- Ascorbate in Myelodysplastic Syndrome (PHASE2)
- Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic Treatment (NA)
- PROTECT-APT 1: Early Treatment and Post-Exposure Prophylaxis of COVID-19 (PHASE2)
- Combined Metabolic Activator Supplementation in Subjects Diagnosed With Alzheimer's Disease (PHASE3)
- 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma (PHASE2)
- Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy (PHASE2)
- Radiofrequency and Exercise-based Rehabilitation on Symptoms Associated With Pelvic Floor Dysfunctions in Breast Cancer (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- water-soluble therapy CI brief — competitive landscape report
- water-soluble therapy updates RSS · CI watch RSS
- University of Virginia portfolio CI
Frequently asked questions about water-soluble therapy
What is water-soluble therapy?
How does water-soluble therapy work?
Who makes water-soluble therapy?
What development phase is water-soluble therapy in?
Related
- Manufacturer: University of Virginia — full pipeline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing