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Water-Based Vaginal Lubricant
A water-based lubricant reduces friction and provides lubrication to vaginal tissues without pharmacological action.
A water-based lubricant reduces friction and provides lubrication to vaginal tissues without pharmacological action. Used for Vaginal dryness and lubrication.
At a glance
| Generic name | Water-Based Vaginal Lubricant |
|---|---|
| Sponsor | University of Texas Southwestern Medical Center |
| Modality | Small molecule |
| Therapeutic area | Gynecology |
| Phase | FDA-approved |
Mechanism of action
Water-based vaginal lubricants work through physical lubrication rather than a drug mechanism, coating vaginal tissues to reduce friction during intercourse or examination. They are absorbed or dispersed over time and provide temporary symptomatic relief of vaginal dryness. This is a medical device/cosmetic product rather than a pharmaceutical drug with a molecular target.
Approved indications
- Vaginal dryness and lubrication
Common side effects
- Local irritation or allergic reaction
- Minimal systemic adverse events expected
Key clinical trials
- Use of Lubricant Gel to Shorten the Second Stage of Labor During Vaginal Delivery (NA)
- Effect of Perineal Massage on the Frequency of Episiotomy and Perineal Tearing (NA)
- Perineal Massage During Labor for the Prevention of Perineal Trauma (NA)
- Effectiveness and Safety of a Water-based and a Silicone-based Personal Lubricants With Sensory Action (NA)
- Vaginal Dehydroepiandrosterone (DHEA) in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors (PHASE2)
- Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women (PHASE1)
- A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening (NA)
- Soft Tissue Release With and Without Vaginal Dilators on Pain and Sexual Function in Genitio Pelvic Pain (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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