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Water based lubricant
Water based lubricant is a Small molecule drug developed by University of Southern California. It is currently FDA-approved for Vaginal lubrication, Medical device lubrication. Also known as: Surgilube (Savage Laboratories), KY gel.
A water-based lubricant reduces friction between surfaces through a thin aqueous film.
A water-based lubricant has been studied in clinical trials for various conditions, including obesity, pelvic floor disorders, and genito-pelvic pain/penetration disorder. The mechanism of action of a water-based lubricant is classified as a small molecule modality, according to ChEMBL, but specific details on its mechanism are not provided.
At a glance
| Generic name | Water based lubricant |
|---|---|
| Also known as | Surgilube (Savage Laboratories), KY gel |
| Sponsor | University of Southern California |
| Modality | Small molecule |
| Therapeutic area | Medical Device/Personal Care |
| Phase | FDA-approved |
Mechanism of action
Water-based lubricants work by creating a hydrophilic layer that minimizes direct contact and friction between surfaces. The water component provides lubrication while remaining compatible with most materials and being easily washable. These lubricants are commonly used in medical, personal care, and industrial applications where biocompatibility and ease of cleanup are important.
Approved indications
- Vaginal lubrication
- Medical device lubrication
Common side effects
- Local irritation
- Allergic contact dermatitis
Key clinical trials
- Mobilization and Outcomes After Venous Closure
- Use of Lubricant Gel to Shorten the Second Stage of Labor During Vaginal Delivery (NA)
- Effect of Perineal Massage on the Frequency of Episiotomy and Perineal Tearing (NA)
- Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT) (NA)
- Perineal Massage During Labor for the Prevention of Perineal Trauma (NA)
- Hyaluronic Acid for Prevention of Post-Intubation Sore Throat and Hoarseness (NA)
- Comparison Using a VLS Using GlideRite Stylet Versus TCI Articulating Introducer in Predictive Difficult Intubation (NA)
- Effectiveness and Safety of a Water-based and a Silicone-based Personal Lubricants With Sensory Action (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Water based lubricant CI brief — competitive landscape report
- Water based lubricant updates RSS · CI watch RSS
- University of Southern California portfolio CI
Frequently asked questions about Water based lubricant
What is Water based lubricant?
How does Water based lubricant work?
What is Water based lubricant used for?
Who makes Water based lubricant?
Is Water based lubricant also known as anything else?
What development phase is Water based lubricant in?
What are the side effects of Water based lubricant?
Related
- Manufacturer: University of Southern California — full pipeline
- Therapeutic area: All drugs in Medical Device/Personal Care
- Indication: Drugs for Vaginal lubrication
- Indication: Drugs for Medical device lubrication
- Also known as: Surgilube (Savage Laboratories), KY gel
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing