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Vitamin D: liquid form, start weekly
Vitamin D acts as a steroid hormone that binds to the vitamin D receptor to regulate calcium and phosphate homeostasis, immune function, and cell differentiation.
Vitamin D acts as a steroid hormone that binds to the vitamin D receptor to regulate calcium and phosphate homeostasis, immune function, and cell differentiation. Used for Vitamin D deficiency, Hypocalcemia, Osteomalacia.
At a glance
| Generic name | Vitamin D: liquid form, start weekly |
|---|---|
| Also known as | Vitamin D3 Streuli |
| Sponsor | University Hospital, Basel, Switzerland |
| Drug class | Vitamin/steroid hormone |
| Target | Vitamin D receptor (VDR) |
| Modality | Small molecule |
| Therapeutic area | Endocrinology/Bone metabolism/Immunology |
| Phase | FDA-approved |
Mechanism of action
Vitamin D (cholecalciferol or ergocalciferol) is converted in the liver and kidneys to its active form, calcitriol, which binds to the vitamin D receptor (VDR) in target tissues. This activates gene transcription pathways that promote intestinal calcium absorption, bone mineralization, immune regulation, and cellular proliferation control. Vitamin D deficiency impairs these processes, leading to metabolic bone disease and immune dysfunction.
Approved indications
- Vitamin D deficiency
- Hypocalcemia
- Osteomalacia
- Rickets
- Hypoparathyroidism
Common side effects
- Hypercalcemia
- Hypercalciuria
- Nausea
- Vomiting
- Constipation
- Weakness
Key clinical trials
- Vitamin D and Type 2 Diabetes - Treat-To-Target (PHASE3)
- Oral Vitamin D Substitution Weekly or Monthly and Adherence (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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