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Vitamin C,thiamine,hydrocortisone
Vitamin C acts as an antioxidant, thiamine serves as a coenzyme in carbohydrate metabolism, and hydrocortisone is a corticosteroid with anti-inflammatory properties.
Vitamin C acts as an antioxidant, thiamine serves as a coenzyme in carbohydrate metabolism, and hydrocortisone is a corticosteroid with anti-inflammatory properties. Used for Wound healing, Atrial fibrillation for stroke prevention, Immune system disorders.
At a glance
| Generic name | Vitamin C,thiamine,hydrocortisone |
|---|---|
| Also known as | Ascorbic Acid, Vitamin B1 |
| Sponsor | Northern Jiangsu People's Hospital |
| Drug class | Vitamin: Vitamin B complex, Thiamine: Vitamin B1, Hydrocortisone: Corticosteroid |
| Modality | Small molecule |
| Therapeutic area | General Health, Cardiovascular, Immunology |
| Phase | Phase 3 |
Mechanism of action
Vitamin C's antioxidant properties help protect cells from damage, while thiamine plays a crucial role in energy production. Hydrocortisone, a synthetic corticosteroid, mimics the effects of cortisol in the body, reducing inflammation and suppressing the immune system.
Approved indications
- Wound healing, Atrial fibrillation for stroke prevention, Immune system disorders
Common side effects
- Nausea
- Dizziness
- Headache
Key clinical trials
- Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors (PHASE2)
- Effects of Intravenous Metabolic Recovery Agent in Elderly Septic Patients on Prognosis and Microcirculation. (NA)
- Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (PHASE1, PHASE2)
- Vitamin C, Hydrocortisone and Thiamine for Septic Shock (PHASE2)
- Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock (NA)
- HAT for the Treatment of Sepsis Associated With NASTI (PHASE1, PHASE2)
- Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock (PHASE3)
- Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock. (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
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