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Vitamin A + Zinc
Vitamin A and zinc work synergistically to support immune function and mucosal barrier integrity, enhancing resistance to infections.
Vitamin A and zinc work synergistically to support immune function and mucosal barrier integrity, enhancing resistance to infections. Used for Reduction of infection morbidity and mortality in children with vitamin A and zinc deficiency, Immune support in resource-limited settings with high infectious disease burden.
At a glance
| Generic name | Vitamin A + Zinc |
|---|---|
| Sponsor | National Institute of Allergy and Infectious Diseases (NIAID) |
| Drug class | Micronutrient supplement combination |
| Modality | Small molecule |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Vitamin A (retinol) is essential for maintaining epithelial cell differentiation and immune cell development, particularly T cells and antibody-producing B cells. Zinc is a critical cofactor for numerous immune enzymes and proteins, supporting both innate and adaptive immunity. Together, these micronutrients enhance immune response and reduce infection risk, particularly in populations with deficiency.
Approved indications
- Reduction of infection morbidity and mortality in children with vitamin A and zinc deficiency
- Immune support in resource-limited settings with high infectious disease burden
Common side effects
- Nausea
- Gastrointestinal upset
- Hypervitaminosis A (with excessive dosing)
Key clinical trials
- Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome. (NA)
- Child Health, Agriculture and Integrated Nutrition (NA)
- A Study Evaluating Quality of Life Parameters Following Use of Emergen-C (PHASE4)
- A Clinical Trial to Investigate the Safety and Efficacy of Papillex® on Abnormal Cervical Cells Caused by HPV. (NA)
- Assessing the Impact of Herbal Supplement on Fatigue and Disease Activity in SLE: Results From an 8-Week Randomized Trial (NA)
- Effectiveness of Pulsed Electromagnetic Fields and Nutraceutical Supplementation in Women With Distal Radius Fracture (NA)
- Chemo Brain Prehab Project (NA)
- Alii Supplement Study (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vitamin A + Zinc CI brief — competitive landscape report
- Vitamin A + Zinc updates RSS · CI watch RSS
- National Institute of Allergy and Infectious Diseases (NIAID) portfolio CI