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Very Low Nicotine Content Cigarettes
Very Low Nicotine Content Cigarettes work by reducing the amount of nicotine in cigarettes, thereby decreasing the addictive potential and harm associated with smoking.
Very Low Nicotine Content Cigarettes work by reducing the amount of nicotine in cigarettes, thereby decreasing the addictive potential and harm associated with smoking. Used for Reducing nicotine intake in smokers.
At a glance
| Generic name | Very Low Nicotine Content Cigarettes |
|---|---|
| Also known as | Reduced Nicotine Content Cigarettes |
| Sponsor | University of Minnesota |
| Modality | Small molecule |
| Therapeutic area | Addiction |
| Phase | Phase 3 |
Mechanism of action
This is achieved through a reduction in the nicotine content of the cigarettes, which can help smokers reduce their nicotine intake and eventually quit smoking. The exact mechanism of action is not well understood, but it is believed to involve a combination of behavioral and physiological changes.
Approved indications
- Reducing nicotine intake in smokers
Common side effects
- Nicotine withdrawal symptoms
Key clinical trials
- Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing (NA)
- Opioids, Low Nicotine Cigarettes, and Chronic Pain (NA)
- Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration (PHASE2)
- Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers (NA)
- Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women (PHASE1, PHASE2)
- Cardiovascular Effects of Very Low Nicotine Content Cigarettes (EARLY_PHASE1)
- Low Nicotine Cigarettes Plus Electronic Cigarettes (NA)
- Low Nicotine Cigarettes, Smoking, and Chronic Pain (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Very Low Nicotine Content Cigarettes CI brief — competitive landscape report
- Very Low Nicotine Content Cigarettes updates RSS · CI watch RSS
- University of Minnesota portfolio CI