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vehicle plaster
A vehicle plaster is a transdermal delivery system that uses a plaster or patch base to transport and release pharmaceutical agents through the skin.
At a glance
| Generic name | vehicle plaster |
|---|---|
| Sponsor | Beijing Tiantan Hospital |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Vehicle plasters function as topical formulations designed to adhere to skin and provide sustained or controlled release of active pharmaceutical ingredients across the dermal barrier. The plaster matrix serves as both an adhesive base and a reservoir for the drug, allowing for prolonged local or systemic delivery. This delivery method is commonly used to improve patient compliance and reduce dosing frequency compared to oral or injectable alternatives.
Approved indications
Common side effects
- Skin irritation at application site
- Contact dermatitis
Key clinical trials
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |