Last reviewed 2026-04-23 · How we verify

Vaxzevria Vaccine

Vaxzevria Vaccine works by stimulating the body's immune system to produce a specific response against the SARS-CoV-2 virus.

Vaxzevria Vaccine works by stimulating the body's immune system to produce a specific response against the SARS-CoV-2 virus. Used for COVID-19 prevention.

At a glance

Mechanism of action

This is achieved through the introduction of a weakened or inactivated form of the virus, which triggers an immune response without causing the disease itself. The immune system then produces antibodies and immune cells that can recognize and attack the virus if it enters the body in the future.

Approved indications

• COVID-19 prevention

Common side effects

• Pain, redness, or swelling at the injection site
• Fatigue
• Headache
• Muscle pain
• Chills

Key clinical trials

• Does Repeat Influenza Vaccination Constrain Influenza Immune Responses and Protection
• Mix and Match of the COVID-19 Vaccine for Safety and Immunogenicity (PHASE2)
• Evaluation of COVID-19 Vaccines Given as a Booster in Healthy Adults in Indonesia (MIACoV Indonesia) (PHASE3)
• COVID-19 Fourth Dose Study in Australia (PHASE3)
• Adaptive Immune Response to COVID-19 Vaccination
• Immunogenicity and Safety Study of SCB-2019 Vaccine as a Booster to COVID-19 Vaccine in Adults (PHASE3)
• SafeTy and Efficacy of Preventative CoVID Vaccines
• Vaccination Against COVID-19 in Pregnant and Lactating Women in Belgium

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Vaxzevria Vaccine CI brief — competitive landscape report
• Vaxzevria Vaccine updates RSS · CI watch RSS
• Clover Biopharmaceuticals AUS Pty portfolio CI