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Vasoactive drug therapies
Vasoactive drug therapies is a Vasoactive agent / Sympathomimetic Small molecule drug developed by Gruppo Italiano Multidisciplinare per lo Studio della Sincope. It is currently in Phase 3 development for Syncope prevention and management (vasovagal syncope, orthostatic hypotension). Also known as: Antihypertensive, Nitrates, Alpha-antagonists, Diuretics.
Vasoactive drug therapies work by modulating vascular tone and blood pressure through sympathomimetic or vasodilatory mechanisms to prevent syncope and improve cardiovascular stability.
Vasoactive drug therapies work by modulating vascular tone and blood pressure through sympathomimetic or vasodilatory mechanisms to prevent syncope and improve cardiovascular stability. Used for Syncope prevention and management (vasovagal syncope, orthostatic hypotension).
At a glance
| Generic name | Vasoactive drug therapies |
|---|---|
| Also known as | Antihypertensive, Nitrates, Alpha-antagonists, Diuretics, Neuroleptic antidepressant |
| Sponsor | Gruppo Italiano Multidisciplinare per lo Studio della Sincope |
| Drug class | Vasoactive agent / Sympathomimetic |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
Vasoactive agents increase peripheral vascular resistance and/or cardiac output to maintain adequate cerebral perfusion pressure, thereby preventing the sudden drops in blood pressure that lead to syncope. These drugs may act through alpha-adrenergic stimulation, beta-adrenergic effects, or direct vasodilation depending on the specific agent used. In the context of syncope management, they are typically employed to counteract vasovagal or orthostatic mechanisms.
Approved indications
- Syncope prevention and management (vasovagal syncope, orthostatic hypotension)
Common side effects
- Hypertension
- Tachycardia
- Tremor
- Anxiety
- Headache
Key clinical trials
- Research on Circulation Management Strategy Based on Oxygen Metabolism Balance After CHD Surgery (NA)
- Investigation Into Detection of Prostate Cancer Using Voided Urine (Prostate VPAC)
- CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock (PHASE2)
- International Care Bundle Evaluation in Cerebral Hemorrhage Research (PHASE4)
- Correlation Between EIT-based Pulse Wave Method for Pulmonary Perfusion Monitoring and Pulmonary Artery Catheter-based Stroke Volume Measurement
- Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (NA)
- Evaluation of Hemodynamics in People With Untreated Preeclampsia Using Echocardiography
- Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vasoactive drug therapies CI brief — competitive landscape report
- Vasoactive drug therapies updates RSS · CI watch RSS
- Gruppo Italiano Multidisciplinare per lo Studio della Sincope portfolio CI
Frequently asked questions about Vasoactive drug therapies
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Related
- Drug class: All Vasoactive agent / Sympathomimetic drugs
- Manufacturer: Gruppo Italiano Multidisciplinare per lo Studio della Sincope — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Syncope prevention and management (vasovagal syncope, orthostatic hypotension)
- Also known as: Antihypertensive, Nitrates, Alpha-antagonists, Diuretics, Neuroleptic antidepressant
- Compare: Vasoactive drug therapies vs similar drugs
- Pricing: Vasoactive drug therapies cost, discount & access