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Dipropylacetamide (VALPROMIDE)

Phase 2 active Small molecule ✓ Verified May 2026

Dipropylacetamide (generic name: VALPROMIDE) is a valpromide drug. It is currently in Phase 2 development.

Valpromide works by modulating the activity of certain neurotransmitters in the brain.

Dipropylacetamide is an anti-epileptic drug that has been studied in clinical trials for the treatment of epilepsy. It has also been investigated in relation to drug hypersensitivity syndrome.

Likelihood of approval
12.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • CNS / neurology attrition -3.0pp
    CNS drugs have historically high Phase 3 failure rates (notably in Alzheimer disease + major depression).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameVALPROMIDE
Drug classvalpromide
ModalitySmall molecule
Therapeutic areaNeuroscience
PhasePhase 2

Mechanism of action

Think of neurotransmitters like messengers that help different parts of the brain talk to each other. Valpromide helps regulate the amount of these messengers, which can help balance brain activity and treat certain conditions. By doing so, it can help reduce symptoms of anxiety, depression, and other mental health conditions.

Approved indications

No approved indications tracked.

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Dipropylacetamide

What is Dipropylacetamide?

Dipropylacetamide (VALPROMIDE) is a valpromide drug.

How does Dipropylacetamide work?

Valpromide works by modulating the activity of certain neurotransmitters in the brain.

What is the generic name of Dipropylacetamide?

VALPROMIDE is the generic (nonproprietary) name of Dipropylacetamide.

What drug class is Dipropylacetamide in?

Dipropylacetamide belongs to the valpromide class. See all valpromide drugs at /class/valpromide.

What development phase is Dipropylacetamide in?

Dipropylacetamide is in Phase 2.

What are the side effects of Dipropylacetamide?

Common side effects of Dipropylacetamide include Poisoning deliberate, Coma, Hypothermia, Toxicity to various agents, Suicide attempt, Meningioma.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing