Last reviewed · How we verify
use of sulodexide orally only
use of sulodexide orally only is a Glycosaminoglycan anticoagulant Small molecule drug developed by Sun Yat-sen University. It is currently FDA-approved for Chronic venous insufficiency, Diabetic angiopathy, Thrombotic disorders. Also known as: oral use of sulodexide.
Sulodexide is a glycosaminoglycan that enhances fibrinolysis and inhibits thrombosis by modulating coagulation and fibrinolytic pathways.
Sulodexide is a glycosaminoglycan that enhances fibrinolysis and inhibits thrombosis by modulating coagulation and fibrinolytic pathways. Used for Chronic venous insufficiency, Diabetic angiopathy, Thrombotic disorders.
At a glance
| Generic name | use of sulodexide orally only |
|---|---|
| Also known as | oral use of sulodexide |
| Sponsor | Sun Yat-sen University |
| Drug class | Glycosaminoglycan anticoagulant |
| Target | Antithrombin III, Heparin cofactor II |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Sulodexide is a mixture of fast-moving heparin and dermatan sulfate that works through multiple anticoagulant and antithrombotic mechanisms. It enhances the activity of antithrombin III and heparin cofactor II, reduces platelet aggregation, and improves blood flow properties. The drug is used orally to prevent thrombotic events and improve microcirculation in various vascular conditions.
Approved indications
- Chronic venous insufficiency
- Diabetic angiopathy
- Thrombotic disorders
- Microangiopathy
Common side effects
- Bleeding
- Gastrointestinal disturbance
- Bruising
Key clinical trials
- Sulodexide in the Treatment of Chronic Primary Venous Disease of the Lower Extremities (PHASE3)
- Endothelial Function Evaluation in Patients With PAOD Treated With Sulodexide + Conventional Treatment (CT) Vs CT Alone (PHASE3)
- Effect of Sulodexide on Albuminuria in Chinese Type 2 Diabetic Patients (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- use of sulodexide orally only CI brief — competitive landscape report
- use of sulodexide orally only updates RSS · CI watch RSS
- Sun Yat-sen University portfolio CI
Frequently asked questions about use of sulodexide orally only
What is use of sulodexide orally only?
How does use of sulodexide orally only work?
What is use of sulodexide orally only used for?
Who makes use of sulodexide orally only?
Is use of sulodexide orally only also known as anything else?
What drug class is use of sulodexide orally only in?
What development phase is use of sulodexide orally only in?
What are the side effects of use of sulodexide orally only?
What does use of sulodexide orally only target?
Related
- Drug class: All Glycosaminoglycan anticoagulant drugs
- Target: All drugs targeting Antithrombin III, Heparin cofactor II
- Manufacturer: Sun Yat-sen University — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Chronic venous insufficiency
- Indication: Drugs for Diabetic angiopathy
- Indication: Drugs for Thrombotic disorders
- Also known as: oral use of sulodexide
- Compare: use of sulodexide orally only vs similar drugs
- Pricing: use of sulodexide orally only cost, discount & access