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US-guided tenotomy with PRP

Jose Ignacio Martin · Phase 3 active Small molecule Under review

US-guided tenotomy with PRP is a Small molecule drug developed by Jose Ignacio Martin. It is currently in Phase 3 development for Tendinopathy, including Achilles tendonitis and rotator cuff tendinosis. Also known as: pure-PRP (without leukocytes).

US-guided tenotomy with PRP is a minimally invasive procedure that uses ultrasound guidance to release tension in tendons and ligaments, with the addition of platelet-rich plasma (PRP) to promote healing.

US-guided tenotomy with PRP is a treatment that has been studied for chronic epicondylitis, a condition affecting the elbow. This treatment involves using ultrasound guidance to perform a tenotomy, a procedure to cut a tendon, and injecting platelet-rich plasma (PRP) into the affected area.

Likelihood of approval
58.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameUS-guided tenotomy with PRP
Also known aspure-PRP (without leukocytes)
SponsorJose Ignacio Martin
ModalitySmall molecule
Therapeutic areaOrthopedics
PhasePhase 3

Mechanism of action

The procedure involves inserting a small needle under ultrasound guidance to release scar tissue and adhesions in tendons and ligaments. The addition of PRP, which is derived from the patient's own blood, is thought to enhance the healing process by promoting the growth of new tissue and reducing inflammation.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about US-guided tenotomy with PRP

What is US-guided tenotomy with PRP?

US-guided tenotomy with PRP is a Small molecule drug developed by Jose Ignacio Martin, indicated for Tendinopathy, including Achilles tendonitis and rotator cuff tendinosis.

How does US-guided tenotomy with PRP work?

US-guided tenotomy with PRP is a minimally invasive procedure that uses ultrasound guidance to release tension in tendons and ligaments, with the addition of platelet-rich plasma (PRP) to promote healing.

What is US-guided tenotomy with PRP used for?

US-guided tenotomy with PRP is indicated for Tendinopathy, including Achilles tendonitis and rotator cuff tendinosis.

Who makes US-guided tenotomy with PRP?

US-guided tenotomy with PRP is developed by Jose Ignacio Martin (see full Jose Ignacio Martin pipeline at /company/jose-ignacio-martin).

Is US-guided tenotomy with PRP also known as anything else?

US-guided tenotomy with PRP is also known as pure-PRP (without leukocytes).

What development phase is US-guided tenotomy with PRP in?

US-guided tenotomy with PRP is in Phase 3.

What are the side effects of US-guided tenotomy with PRP?

Common side effects of US-guided tenotomy with PRP include Pain, swelling, and bruising at the injection site.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing