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URIDINE TRIACETATE
URIDINE TRIACETATE is a drug. It is currently FDA-approved (first approved 2015).
URIDINE TRIACETATE, also known as RG2133, is a small molecule with an unknown mechanism of action. It has been studied in clinical trials for various conditions, including mitochondrial diseases, pancreatic cancer, and hereditary orotic aciduria.
At a glance
| Generic name | URIDINE TRIACETATE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 2015 |
Approved indications
Common side effects
- Vomiting
- Nausea
- Diarrhea
Serious adverse events
- Grade 3 Nausea and Vomiting
Key clinical trials
- Open-Label Study of Uridine Triacetate in Pediatric Patients With Hereditary Orotic Aciduria (PHASE3)
- Uridine Triacetate as Antidote for Patients at Excess Risk of 5-FU Toxicity Due to Overdosage or Impaired Elimination
- Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer (PHASE3)
- S9915 Triacetyluridine, Fluorouracil, and Leucovorin in Treating Patients With Unresectable, Locally Advanced, or Metastatic Cancer of the Esophagus or Stomach (PHASE2)
- RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease (PHASE1)
- Phase I Study of PN401, Fluorouracil, Leucovorin and CPT-11 in Patients With Solid Tumors (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- URIDINE TRIACETATE CI brief — competitive landscape report
- URIDINE TRIACETATE updates RSS · CI watch RSS
Frequently asked questions about URIDINE TRIACETATE
What is URIDINE TRIACETATE?
When was URIDINE TRIACETATE approved?
What development phase is URIDINE TRIACETATE in?
What are the side effects of URIDINE TRIACETATE?
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing