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urea/lactic acid
Urea and lactic acid work together to soften and exfoliate the stratum corneum while restoring skin hydration and pH balance.
Urea and lactic acid work together to soften and exfoliate the stratum corneum while restoring skin hydration and pH balance. Used for Hyperkeratosis and xerosis (dry, thickened skin), Calluses and corns, Ichthyosis and related keratinization disorders.
At a glance
| Generic name | urea/lactic acid |
|---|---|
| Sponsor | ACO Hud Nordic AB |
| Drug class | Topical keratolytic/emollient |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Urea acts as a keratolytic agent that breaks down and softens hardened, thickened skin by disrupting hydrogen bonds in keratin, while lactic acid provides gentle chemical exfoliation and humectant properties. Together, they improve skin barrier function, increase moisture retention, and promote removal of dead skin cells, making this combination effective for hyperkeratotic and xerotic skin conditions.
Approved indications
- Hyperkeratosis and xerosis (dry, thickened skin)
- Calluses and corns
- Ichthyosis and related keratinization disorders
Common side effects
- Local irritation or burning sensation
- Erythema
- Pruritus
Key clinical trials
- Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction
- Factors Affecting Mortality in Critical Patients Admitted to Intensive Care Unit Due to Coronavirus Disease 2019
- Prospective Validation of a Points Score System Predicting 30-day Survival
- Pancreatic Cancer Screening in a Population at High Risk (NA)
- UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients (PHASE1)
- A Comparative Study Between Neutrophil/Lymphocyte Ratio and Lactate/Albumin Ratio as Predictive Inflammatory Markers for Sepsis
- Predicting 28-Day Survival in OHCA Patients
- Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- urea/lactic acid CI brief — competitive landscape report
- urea/lactic acid updates RSS · CI watch RSS
- ACO Hud Nordic AB portfolio CI