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Typically prescribed oral antibiotic prophylaxis
Oral antibiotics prevent bacterial infection by inhibiting bacterial protein synthesis or cell wall formation.
Oral antibiotics prevent bacterial infection by inhibiting bacterial protein synthesis or cell wall formation. Used for Surgical site infection prophylaxis, Endocarditis prophylaxis in at-risk cardiac patients, Urinary tract infection prophylaxis.
At a glance
| Generic name | Typically prescribed oral antibiotic prophylaxis |
|---|---|
| Also known as | Oral antibiotics |
| Sponsor | Women and Infants Hospital of Rhode Island |
| Drug class | Antibiotic (class varies by specific agent) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Oral antibiotic prophylaxis typically involves agents such as amoxicillin or other beta-lactams that work by disrupting bacterial cell wall integrity, or macrolides/fluoroquinolones that inhibit bacterial protein synthesis. These mechanisms prevent colonization and infection in at-risk patients undergoing procedures or with specific medical conditions.
Approved indications
- Surgical site infection prophylaxis
- Endocarditis prophylaxis in at-risk cardiac patients
- Urinary tract infection prophylaxis
Common side effects
- Gastrointestinal upset (nausea, diarrhea)
- Allergic reaction (rash, urticaria)
- Headache
- Yeast infection (candidiasis)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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