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TRYPAN BLUE
MembraneBlue 0.15% selectively stains membranes in the human eye during posterior surgery.
At a glance
| Generic name | TRYPAN BLUE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 2004 |
Mechanism of action
MembraneBlue 0.15% is used to stain specific membranes in the eye, such as epiretinal membranes (ERM) and Internal Limiting Membranes (ILM), making them more visible during surgical procedures.
Approved indications
Common side effects
- Discoloration of high water content hydrogen intraocular lenses
- Inadvertent staining of the posterior lens capsule
- Staining of the vitreous face
Key clinical trials
- Impact of ILM Peeling in RRD/ I-Peel (NA)
- The Belgian Endothelial Surgical Transplant of the Cornea (NA)
- The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study
- Mechanical Properties of the Internal Limiting Membrane and Intraoperative Utility of Brilliant Blue g (Bbg) and Indocyanine Green (Icg) Assisted Chromovitrectomy
- Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEK (NA)
- Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling) (NA)
- Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract (NA)
- Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids. (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- TRYPAN BLUE CI brief — competitive landscape report
- TRYPAN BLUE updates RSS · CI watch RSS