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Trivalent split Inf

National Institute of Allergy and Infectious Diseases (NIAID) · FDA-approved active Biologic

Trivalent split influenza vaccine stimulates the immune system to produce antibodies against three strains of influenza virus.

Trivalent split influenza vaccine stimulates the immune system to produce antibodies against three strains of influenza virus. Used for Seasonal influenza prevention in adults and children.

At a glance

Generic nameTrivalent split Inf
SponsorNational Institute of Allergy and Infectious Diseases (NIAID)
Drug classInactivated influenza vaccine
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhaseFDA-approved

Mechanism of action

The vaccine contains inactivated (split) viral antigens from three influenza strains (typically two A subtypes and one B type). When administered, these antigens trigger both humoral and cellular immune responses, leading to the production of strain-specific antibodies and memory B cells that provide protection against infection with matching circulating influenza viruses.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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