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Trivalent Influenza Vaccine
Trivalent Influenza Vaccine is a Inactivated influenza vaccine Biologic drug developed by MedImmune LLC. It is currently FDA-approved for Seasonal influenza prevention in adults and children ≥6 months of age. Also known as: Flu shot, Flu vaccination, Fluzone, Fluzone HD.
The trivalent influenza vaccine stimulates the immune system to produce antibodies against three strains of influenza virus, providing protection against seasonal flu infection.
The trivalent influenza vaccine stimulates the immune system to produce antibodies against three strains of influenza virus, providing protection against seasonal flu infection. Used for Seasonal influenza prevention in adults and children ≥6 months of age.
At a glance
| Generic name | Trivalent Influenza Vaccine |
|---|---|
| Also known as | Flu shot, Flu vaccination, Fluzone, Fluzone HD, Fluzone High-dose |
| Sponsor | MedImmune LLC |
| Drug class | Inactivated influenza vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | FDA-approved |
Mechanism of action
This vaccine contains inactivated (killed) influenza virus particles or antigens from three circulating influenza strains (typically two A strains and one B strain). When administered, it triggers both humoral and cellular immune responses, leading to the production of strain-specific antibodies and memory B cells. Upon exposure to wild-type influenza virus, these pre-existing antibodies neutralize the virus and prevent or reduce the severity of infection.
Approved indications
- Seasonal influenza prevention in adults and children ≥6 months of age
Common side effects
- Injection site soreness, redness, or swelling
- Fever
- Myalgia (muscle aches)
- Headache
- Fatigue
Key clinical trials
- Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines (PHASE4)
- Influenza Vaccination Strategy for Patients With Hematologic Malignancy (PHASE3)
- Phase 1/2 Study of a Plant-Based Seasonal Recombinant Trivalent VLP Influenza Vaccine (PHASE1, PHASE2)
- A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults ≥65 Years of Age (PHASE3)
- Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS (PHASE3)
- Post-marketing Surveillance Study for the Safety of Efluelda® Pre-filled Syringe
- A Study on the Safety and Immunogenicity of Influenza, Respiratory Syncytial Virus, Human Metapneumovirus and Parainfluenza Vaccines in Adults 18 to 49 Years of Age. (PHASE1)
- Ibrutinib as an Immune Modulating Agent for Patients With Asymptomatic, High-risk CLL/SLL Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Trivalent Influenza Vaccine CI brief — competitive landscape report
- Trivalent Influenza Vaccine updates RSS · CI watch RSS
- MedImmune LLC portfolio CI
Frequently asked questions about Trivalent Influenza Vaccine
What is Trivalent Influenza Vaccine?
How does Trivalent Influenza Vaccine work?
What is Trivalent Influenza Vaccine used for?
Who makes Trivalent Influenza Vaccine?
Is Trivalent Influenza Vaccine also known as anything else?
What drug class is Trivalent Influenza Vaccine in?
What development phase is Trivalent Influenza Vaccine in?
What are the side effects of Trivalent Influenza Vaccine?
Related
- Drug class: All Inactivated influenza vaccine drugs
- Manufacturer: MedImmune LLC — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Seasonal influenza prevention in adults and children ≥6 months of age
- Also known as: Flu shot, Flu vaccination, Fluzone, Fluzone HD, Fluzone High-dose
- Compare: Trivalent Influenza Vaccine vs similar drugs
- Pricing: Trivalent Influenza Vaccine cost, discount & access