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Psyquil (TRIFLUPROMAZINE)

FDA-approved approved Small molecule ✓ Verified May 2026 Quality 25/100

Psyquil (generic name: TRIFLUPROMAZINE) is a drug. It is currently FDA-approved (first approved 1957) for Nausea, Nausea and vomiting, Psychotic disorder.

Psyquil is a small molecule that acts as a dopamine D2 receptor antagonist. It is classified as an antagonist and has been known by various synonyms, including Triflupromazine.

At a glance

Generic nameTRIFLUPROMAZINE
TargetMultidrug resistance protein 1, 5-hydroxytryptamine receptor 2A, D(2) dopamine receptor
ModalitySmall molecule
Therapeutic areaOther
PhaseFDA-approved
First approval1957

Approved indications

Common side effects

No common side effects on file.

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions

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Frequently asked questions about Psyquil

What is Psyquil?

Psyquil (TRIFLUPROMAZINE) is a Small molecule drug, indicated for Nausea, Nausea and vomiting, Psychotic disorder.

What is Psyquil used for?

Psyquil is indicated for Nausea, Nausea and vomiting, Psychotic disorder, Vomiting.

What is the generic name of Psyquil?

TRIFLUPROMAZINE is the generic (nonproprietary) name of Psyquil.

When was Psyquil approved?

Psyquil was first approved on 1957.

What development phase is Psyquil in?

Psyquil is FDA-approved (marketed).

What does Psyquil target?

Psyquil targets Multidrug resistance protein 1, 5-hydroxytryptamine receptor 2A, D(2) dopamine receptor.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing