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Triamcinolone Acetonide + laser
Triamcinolone acetonide is a corticosteroid that reduces inflammation, combined with laser treatment to mechanically ablate or coagulate tissue, used together to treat retinal conditions.
Triamcinolone acetonide is a corticosteroid that reduces inflammation, combined with laser treatment to mechanically ablate or coagulate tissue, used together to treat retinal conditions. Used for Diabetic macular edema, Retinal vein occlusion with macular edema.
At a glance
| Generic name | Triamcinolone Acetonide + laser |
|---|---|
| Also known as | corticosteroid |
| Sponsor | Jaeb Center for Health Research |
| Drug class | Corticosteroid + laser therapy combination |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
Triamcinolone acetonide suppresses inflammatory cytokines and immune cell infiltration by binding glucocorticoid receptors, reducing edema and inflammation in the retina. Laser photocoagulation simultaneously provides thermal ablation or coagulation of abnormal retinal tissue. The combination approach addresses both the inflammatory component and structural pathology in retinal disease.
Approved indications
- Diabetic macular edema
- Retinal vein occlusion with macular edema
Common side effects
- Elevated intraocular pressure
- Cataract progression
- Endophthalmitis
- Retinal detachment
- Vision loss
Key clinical trials
- Sialendoscopy Versus Photobiomodulation in Prevention of Radiation Induced Xerostomia (NA)
- Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars (NA)
- Different Treatment Modalities for Oral Lichen Plan (PHASE1)
- Fractional Ablative Laser Treatment for Skin Grafts (NA)
- IVB for Post-vitrectomy Hemorrhage in Diabetic Eyes (NA)
- Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery. (NA)
- Fractionated Carbon Dioxide Laser Therapy for Treatment of Peyronie's Disease (NA)
- Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Triamcinolone Acetonide + laser CI brief — competitive landscape report
- Triamcinolone Acetonide + laser updates RSS · CI watch RSS
- Jaeb Center for Health Research portfolio CI