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Traditional antibiotic treatment
Traditional antibiotics inhibit bacterial protein synthesis or cell wall integrity, thereby killing or stopping the growth of susceptible bacteria.
Traditional antibiotics inhibit bacterial protein synthesis or cell wall integrity, thereby killing or stopping the growth of susceptible bacteria. Used for Bacterial infections (broad spectrum, specific indications depend on antibiotic class and susceptibility).
At a glance
| Generic name | Traditional antibiotic treatment |
|---|---|
| Also known as | Conventional treatment |
| Sponsor | Ain Shams University |
| Drug class | Antibiotic (broad class including beta-lactams, aminoglycosides, tetracyclines, macrolides, fluoroquinolones) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Traditional antibiotics work through multiple mechanisms depending on the class: beta-lactams disrupt bacterial cell wall synthesis, aminoglycosides and tetracyclines inhibit protein synthesis, and fluoroquinolones inhibit DNA gyrase. These mechanisms are bactericidal (kill bacteria) or bacteriostatic (stop growth), allowing the immune system to clear the infection.
Approved indications
- Bacterial infections (broad spectrum, specific indications depend on antibiotic class and susceptibility)
Common side effects
- Gastrointestinal disturbance (nausea, diarrhea, vomiting)
- Allergic reactions (rash, urticaria)
- Photosensitivity (tetracyclines)
- Tendinopathy (fluoroquinolones)
- Ototoxicity (aminoglycosides)
Key clinical trials
- Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease (NA)
- Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ (NA)
- Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children (NA)
- Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement (PHASE3)
- Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia (NA)
- NextGen - Clinical Implication of Next Generation Sequencing (PHASE4)
- EARLY Antibiotics aDAptation in Severe Pneumonia(The EARLY ADAPT Study) (NA)
- Trial of Modifications to Radical Prostatectomy (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |