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TQZ2451

Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Phase 3 active Small molecule Under review

TQZ2451 is a small molecule Small molecule drug developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd.. It is currently in Phase 3 development for Metastatic non-small cell lung cancer.

TQZ2451 is a small molecule drug that targets the molecular target.

TQZ2451 is a treatment being studied in a Phase III clinical trial for Type 2 Diabetes. The trial compares the efficacy and safety of TQZ2451 to Victoza (Liraglutide) and Metformin Hydrochloride in treating Type 2 Diabetes.

Likelihood of approval
61.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Oncology Phase 3 boost +3.0pp
    Oncology Phase 3 trials have higher approval rates (~61%) than the cross-industry average due to clearer endpoints and FDA oncology pathway.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameTQZ2451
SponsorChia Tai Tianqing Pharmaceutical Group Co., Ltd.
Drug classsmall molecule
Targettarget molecular target
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 3

Mechanism of action

TQZ2451 works by binding to the molecular target, which results in the desired therapeutic effect.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about TQZ2451

What is TQZ2451?

TQZ2451 is a small molecule drug developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd., indicated for Metastatic non-small cell lung cancer.

How does TQZ2451 work?

TQZ2451 is a small molecule drug that targets the molecular target.

What is TQZ2451 used for?

TQZ2451 is indicated for Metastatic non-small cell lung cancer.

Who makes TQZ2451?

TQZ2451 is developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (see full Chia Tai Tianqing Pharmaceutical Group Co., Ltd. pipeline at /company/chia-tai-tianqing-pharmaceutical-group-co-ltd).

What drug class is TQZ2451 in?

TQZ2451 belongs to the small molecule class. See all small molecule drugs at /class/small-molecule.

What development phase is TQZ2451 in?

TQZ2451 is in Phase 3.

What are the side effects of TQZ2451?

Common side effects of TQZ2451 include nausea, fatigue, diarrhea.

What does TQZ2451 target?

TQZ2451 targets target molecular target and is a small molecule.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing