Last reviewed 2026-04-23 · How we verify

topical triamcinolone acetonide

Triamcinolone acetonide is a synthetic corticosteroid that works by inhibiting the release of inflammatory mediators.

Triamcinolone acetonide is a synthetic corticosteroid that works by inhibiting the release of inflammatory mediators. Used for Severe skin conditions such as psoriasis, eczema, and dermatitis.

At a glance

Mechanism of action

It does this by binding to glucocorticoid receptors, which then translocate to the nucleus and inhibit the transcription of pro-inflammatory genes. This leads to a reduction in inflammation and immune response.

Approved indications

• Severe skin conditions such as psoriasis, eczema, and dermatitis

Common side effects

• Skin atrophy
• Hypersensitivity reactions

Key clinical trials

• Bladder Directed vs. Pelvic Floor Therapy in IC/BPS (PHASE2)
• Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants (PHASE2)
• Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata (PHASE4)
• Topical Cryotherapy and Keloid/Hypertrophic Scars (PHASE3)
• Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus (PHASE2)
• TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus (PHASE2)
• Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis (PHASE4)
• Palatal Wound Healing After Free Gingival Graft Surgery (NA)

Primary sources

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