Last reviewed · How we verify
Topical hemostat
Topical hemostats work by physically obstructing blood flow to a wound site, thereby facilitating clotting and stopping bleeding.
Topical hemostats work by physically obstructing blood flow to a wound site, thereby facilitating clotting and stopping bleeding. Used for Control of bleeding during surgery.
At a glance
| Generic name | Topical hemostat |
|---|---|
| Sponsor | Ethicon, Inc. |
| Drug class | Topical hemostat |
| Modality | Biologic |
| Therapeutic area | Surgical |
| Phase | Phase 3 |
Mechanism of action
They typically contain a combination of ingredients such as collagen, gelatin, or other substances that help to constrict blood vessels and promote platelet aggregation, ultimately leading to the formation of a stable clot. This process is essential for preventing excessive blood loss and promoting wound healing.
Approved indications
- Control of bleeding during surgery
Common side effects
- Skin irritation
Key clinical trials
- IEIK13 For Neurosurgery (NA)
- Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis (PHASE4)
- SURGICEL® Powder in Controlling Mild or Moderate Parenchymal or Soft Tissue Intraoperative Bleeding in Adult Subjects (NA)
- The SURGICEL® Powder Mild or Moderate Parenchymal or Soft Tissue Intraoperative Bleeding (China Study) (NA)
- Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding (PHASE2, PHASE3)
- Topical Raplixa for Surgical Bleeding in Children (PHASE2)
- Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel) (NA)
- Safety and Performance Evaluation of the Topical Hemostatic Device (AC5™) Following Excision of Skin Lesions (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Topical hemostat CI brief — competitive landscape report
- Topical hemostat updates RSS · CI watch RSS
- Ethicon, Inc. portfolio CI