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Topical agents
Topical agents work by directly applying a medication to the skin to treat various conditions.
Topical agents work by directly applying a medication to the skin to treat various conditions. Used for Eczema, Acne, Wound healing.
At a glance
| Generic name | Topical agents |
|---|---|
| Sponsor | Amgen |
| Drug class | Topical agents |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Topical agents are designed to deliver a specific medication directly to the affected area, reducing systemic side effects and improving efficacy. They can be formulated in various forms, such as creams, ointments, or gels, and are often used to treat skin conditions like eczema, acne, or wounds.
Approved indications
- Eczema
- Acne
- Wound healing
Common side effects
- Skin irritation
- Allergic reactions
- Dryness
Key clinical trials
- Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia (PHASE2)
- A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Cutaneous Venous Malformations (PHASE2)
- Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection (PHASE1, PHASE2)
- Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) (PHASE2)
- Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas (PHASE4)
- Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration
- SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (PHASE3)
- Comparison of 4 Methods of Eye Drops for Pupil Dilation in Diabetic Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Topical agents CI brief — competitive landscape report
- Topical agents updates RSS · CI watch RSS
- Amgen portfolio CI