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Toothpaste Preparation
A toothpaste formulation that mechanically and chemically removes plaque, prevents dental caries, and promotes oral hygiene through abrasive and antimicrobial components.
A toothpaste formulation that mechanically and chemically removes plaque, prevents dental caries, and promotes oral hygiene through abrasive and antimicrobial components. Used for Dental caries prevention, Plaque removal and oral hygiene.
At a glance
| Generic name | Toothpaste Preparation |
|---|---|
| Sponsor | Dr. D. Y. Patil Dental College & Hospital |
| Modality | Small molecule |
| Therapeutic area | Dental/Oral Health |
| Phase | Phase 3 |
Mechanism of action
Toothpaste preparations typically contain abrasive agents (silica, calcium carbonate) that mechanically remove biofilm and food debris, fluoride or other active ingredients that strengthen enamel and inhibit bacterial acid production, and surfactants that aid in cleaning. The formulation may include antimicrobial agents to reduce oral pathogens and desensitizing agents for tooth sensitivity management.
Approved indications
- Dental caries prevention
- Plaque removal and oral hygiene
Common side effects
- Tooth sensitivity
- Gingival irritation
- Allergic contact dermatitis (rare)
Key clinical trials
- Diagnostic Accuracy of Cold, Heat, and Electric Pulp Tests
- Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children (NA)
- Oral Care Strategies for Stroke Patients with Dysphagia (NA)
- Efficacy of Herbal Dentifrice for Management of Dentinal Hypersensitivity (PHASE3)
- Early Caries Lesion Management Observational Study
- The Effects of Ankaferd Blood Stopper (NA)
- Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions (NA)
- Survival Rate and Cost-effectiveness of Conventional vs ART Restorations in a School Setting (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Toothpaste Preparation CI brief — competitive landscape report
- Toothpaste Preparation updates RSS · CI watch RSS
- Dr. D. Y. Patil Dental College & Hospital portfolio CI