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thoracic epidural analgesia
Thoracic epidural analgesia delivers local anesthetic and/or opioid medications into the epidural space of the thoracic spine to block pain signals from the chest and upper abdomen.
Thoracic epidural analgesia delivers local anesthetic and/or opioid medications into the epidural space of the thoracic spine to block pain signals from the chest and upper abdomen. Used for Perioperative pain management in thoracic surgery, Perioperative pain management in upper abdominal surgery, Chronic pain conditions of the thorax and upper abdomen.
At a glance
| Generic name | thoracic epidural analgesia |
|---|---|
| Also known as | Thoracic Epidural Anesthesia, TEA, Thoracic Epidural |
| Sponsor | Volgograd State Medical University |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
This is a regional anesthesia technique rather than a systemically administered drug. Medications injected into the thoracic epidural space diffuse across the dura mater to block nerve roots and spinal cord segments, providing localized pain relief without the systemic effects of general anesthesia or high-dose systemic opioids. It is commonly used for perioperative pain management in thoracic and upper abdominal surgeries.
Approved indications
- Perioperative pain management in thoracic surgery
- Perioperative pain management in upper abdominal surgery
- Chronic pain conditions of the thorax and upper abdomen
Common side effects
- Hypotension
- Urinary retention
- Pruritus
- Nausea
- Epidural hematoma (rare)
- Epidural abscess (rare)
Key clinical trials
- Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (NA)
- Evaluating the Effectiveness of Postoperative Analgesic Methods in Thoracotomy Cases
- Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Liver Resection Surgery (NA)
- General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia (NA)
- Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery (PHASE3)
- Thoracic Epidural Analgesia With Bilateral Erector Spinae Plane Block in Radical Cystectomy Surgery (NA)
- PAravertebral CaTheter Versus Epidural Analgesia in Totally Minimally Invasive Esophagectomies (NA)
- Intraoperative Cryoanalgesia Versus Thoracic Epidural Block in MIRPE (Minimally Invasive Repair of Pectus Excavatum) (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- thoracic epidural analgesia CI brief — competitive landscape report
- thoracic epidural analgesia updates RSS · CI watch RSS
- Volgograd State Medical University portfolio CI