Last reviewed · How we verify
TETRACYCLINE HYDROCHLORIDE
At a glance
| Generic name | TETRACYCLINE HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 1953 |
Approved indications
Common side effects
- Diarrhea
- Nausea
- Headache
- Abnormal feces
- Dysgeusia
- Dyspepsia
- Vomiting
- Abdominal pain
- Constipation
- Anorexia
- Metallic taste
- Furry tongue
Serious adverse events
- Reversible neutropenia (leucopenia)
- Reversible thrombocytopenia
- QT prolongation
- Acute generalized exanthematous pustulosis (AGEP)
- Convulsive seizures
- Encephalopathy
- Aseptic meningitis
- Optic neuropathy
- Peripheral neuropathy
- Pancreatitis
Key clinical trials
- Minocycline in Stroke Study at Maimonides (PHASE2, PHASE3)
- Minocycline Efficacy in Improving Neurological Outcome of Patients Who Undergo Endovascular Revascularization for Acute Ischemic Stroke (PHASE2)
- Antihypertensive Mechanisms of Minocycline in Resistant Hypertension (PHASE4)
- Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Evaluating the Role of Neuroinflammation in Low Back Pain (PHASE2)
- Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma (PHASE2)
- Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry (PHASE4)
- Efficacy and Safety of Minocycline in Acute Spontaneous Intracerebral Hemorrhage (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |