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Testosterone MD-Lotion
Testosterone MD-Lotion delivers testosterone through the skin to replace deficient levels in the body.
Testosterone MD-Lotion delivers testosterone through the skin to replace deficient levels in the body. Used for Hypogonadism in adult males.
At a glance
| Generic name | Testosterone MD-Lotion |
|---|---|
| Also known as | LY900011, Axiron |
| Sponsor | Acrux DDS Pty Ltd |
| Drug class | Androgen replacement therapy |
| Modality | Small molecule |
| Therapeutic area | Endocrinology |
| Phase | Phase 3 |
Mechanism of action
This topical lotion is designed to bypass the gastrointestinal tract and liver, allowing for direct absorption into the bloodstream via the skin, thereby restoring physiological levels of testosterone in hypogonadal men.
Approved indications
- Hypogonadism in adult males
Common side effects
- Acne
- Increased red blood cell count
Key clinical trials
- A Titration Trial to Determine the Effectiveness of Testosterone MD-Lotion (Cutaneous Solution) Formulations (PHASE3)
- A Study of the Pharmacokinetics of Testosterone Metered Dose (MD)-Lotion Formulations (PHASE2)
- A Trial to Evaluate the Ongoing Skin Safety of Testosterone MD-Lotion Formulations (PHASE3)
- A Study to Evaluate the Potential for Interpersonal Transfer of Testosterone Following Single Dose Application
- Testosterone MD-Lotion Residual Washing Study (PHASE1)
- To Determine the Effects of Deodorant, Antiperspirant and Washing on the Pharmacokinetics of 2% Testosterone MD Lotion (PHASE1)
- Pharmacokinetics of Testosterone Lotion in the Treatment of Hypogonadal Males (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Testosterone MD-Lotion CI brief — competitive landscape report
- Testosterone MD-Lotion updates RSS · CI watch RSS
- Acrux DDS Pty Ltd portfolio CI