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Terlipressin and Noradrenaline

Post Graduate Institute of Medical Education and Research, Chandigarh · Phase 3 active Small molecule

Terlipressin and Noradrenaline is a Vasopressin analogue and catecholamine Small molecule drug developed by Post Graduate Institute of Medical Education and Research, Chandigarh. It is currently in Phase 3 development for Severe hypotension and shock.

Terlipressin is a vasopressin analogue that acts as a vasoconstrictor, while noradrenaline is a catecholamine that acts as a vasoconstrictor and increases blood pressure.

Terlipressin is a vasopressin analogue that acts as a vasoconstrictor, while noradrenaline is a catecholamine that acts as a vasoconstrictor and increases blood pressure. Used for Severe hypotension and shock.

At a glance

Generic nameTerlipressin and Noradrenaline
SponsorPost Graduate Institute of Medical Education and Research, Chandigarh
Drug classVasopressin analogue and catecholamine
TargetV1A receptor and alpha-adrenergic receptor
ModalitySmall molecule
Therapeutic areaCardiovascular
PhasePhase 3

Mechanism of action

Terlipressin works by stimulating the V1A receptors on vascular smooth muscle cells, causing vasoconstriction and increased blood pressure. Noradrenaline also acts on the alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. This combination of drugs is used to treat severe hypotension and shock.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Terlipressin and Noradrenaline

What is Terlipressin and Noradrenaline?

Terlipressin and Noradrenaline is a Vasopressin analogue and catecholamine drug developed by Post Graduate Institute of Medical Education and Research, Chandigarh, indicated for Severe hypotension and shock.

How does Terlipressin and Noradrenaline work?

Terlipressin is a vasopressin analogue that acts as a vasoconstrictor, while noradrenaline is a catecholamine that acts as a vasoconstrictor and increases blood pressure.

What is Terlipressin and Noradrenaline used for?

Terlipressin and Noradrenaline is indicated for Severe hypotension and shock.

Who makes Terlipressin and Noradrenaline?

Terlipressin and Noradrenaline is developed by Post Graduate Institute of Medical Education and Research, Chandigarh (see full Post Graduate Institute of Medical Education and Research, Chandigarh pipeline at /company/post-graduate-institute-of-medical-education-and-research-chandigarh).

What drug class is Terlipressin and Noradrenaline in?

Terlipressin and Noradrenaline belongs to the Vasopressin analogue and catecholamine class. See all Vasopressin analogue and catecholamine drugs at /class/vasopressin-analogue-and-catecholamine.

What development phase is Terlipressin and Noradrenaline in?

Terlipressin and Noradrenaline is in Phase 3.

What are the side effects of Terlipressin and Noradrenaline?

Common side effects of Terlipressin and Noradrenaline include Hypertension, Tachycardia, Headache.

What does Terlipressin and Noradrenaline target?

Terlipressin and Noradrenaline targets V1A receptor and alpha-adrenergic receptor and is a Vasopressin analogue and catecholamine.

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