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TENAPANOR HYDROCHLORIDE ›
Regulatory · United States
Marketing authorisations
FDA — authorised 17 October 2023
Application: NDA213931
Marketing authorisation holder: ARDELYX INC
Local brand name: XPHOZAH
Indication: TABLET — ORAL
Status: approved
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FDA
Safety signals — FAERS
Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.
Window: 20 April 2025 – 20 April 2026
Total reports: 198
Most-reported reactions
Diarrhoea — 73 reports (36.87%) Off Label Use — 30 reports (15.15%) Hospitalisation — 20 reports (10.1%) Death — 17 reports (8.59%) Cardiac Failure — 11 reports (5.56%) Peritonitis — 11 reports (5.56%) Cerebral Infarction — 10 reports (5.05%) Fall — 9 reports (4.55%) Shunt Occlusion — 9 reports (4.55%) Hyperkalaemia — 8 reports (4.04%)
Source database →
TENAPANOR HYDROCHLORIDE in other countries
Same drug, different regulators. Each page below lists the local marketing authorisation, HTA position, pricing, and adverse-event data.
Frequently asked questions
Is TENAPANOR HYDROCHLORIDE approved in United States?
Yes. FDA authorised it on 17 October 2023; FDA has authorised it.
Who is the marketing authorisation holder for TENAPANOR HYDROCHLORIDE in United States?
ARDELYX INC holds the US marketing authorisation.