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Technetium99
Technetium-99m is a radioactive tracer that emits gamma radiation, allowing visualization of specific tissues and organs through nuclear imaging.
Technetium-99m is a radioactive tracer that emits gamma radiation, allowing visualization of specific tissues and organs through nuclear imaging. Used for Myocardial perfusion imaging, Bone scintigraphy, Renal imaging.
At a glance
| Generic name | Technetium99 |
|---|---|
| Also known as | Technetium99 sulfur colloid, NANOCIS |
| Sponsor | Milton S. Hershey Medical Center |
| Drug class | Radioactive diagnostic agent / Radiopharmaceutical |
| Modality | Small molecule |
| Therapeutic area | Diagnostic Imaging / Nuclear Medicine |
| Phase | Phase 3 |
Mechanism of action
Technetium-99m is a metastable isotope of technetium that decays by isomeric transition, emitting gamma rays detectable by gamma cameras and SPECT systems. It is conjugated to various radiopharmaceutical compounds that target specific organs or pathological processes, enabling diagnostic imaging of perfusion, function, and pathology. The short half-life (6 hours) and favorable radiation dosimetry make it ideal for clinical nuclear medicine applications.
Approved indications
- Myocardial perfusion imaging
- Bone scintigraphy
- Renal imaging
- Hepatobiliary imaging
- Lung ventilation/perfusion imaging
Common side effects
- Radiation exposure
- Allergic reaction to radiopharmaceutical preparation
Key clinical trials
- EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers (PHASE2)
- Evaluate the Implementation of Using Indocyanine Green for Sentinel Lymph Node Mapping in Breast Cancer Patients (NA)
- Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer (NA)
- Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O) (NA)
- Selective Sentinella Lymph Node Biopsy with Indocyanine Green in Patients with Breast Cancer
- A French Observational Study of Indocyanine Green for Patients With Breast Cancer Having a Sentinel Lymph Node Biopsy.
- Premarking of Axillary Nodes Before Start of Neoadjuvant Chemotherapy Using Magnetic Approach (NA)
- Sentinel Lymph Node Localisation With an Ultra-low Dose of Magtrace in Breast Cancer Patients (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |