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TAP Block Group
TAP block is a regional anesthesia technique that infiltrates local anesthetic into the transversus abdominis plane to block sensory nerves supplying the abdominal wall.
TAP block is a regional anesthesia technique that infiltrates local anesthetic into the transversus abdominis plane to block sensory nerves supplying the abdominal wall. Used for Perioperative analgesia for abdominal surgery, Postoperative pain management following abdominal procedures.
At a glance
| Generic name | TAP Block Group |
|---|---|
| Also known as | 0.25% Bupivacaine, transversus abdominis plane, abdominal muscle anesthesia, TAP, Bupivacaine 0.5%, Ropivacaine with Epinephrine |
| Sponsor | Mayo General Hospital, Ireland |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
The TAP block targets the nerves (T6-L1) that run between the internal oblique and transversus abdominis muscles of the abdominal wall. By depositing local anesthetic in this anatomical plane, the procedure provides anesthesia and analgesia to the abdominal wall without affecting visceral innervation. This technique is used perioperatively to reduce pain and opioid requirements.
Approved indications
- Perioperative analgesia for abdominal surgery
- Postoperative pain management following abdominal procedures
Common side effects
- Local anesthetic toxicity
- Bowel/organ perforation
- Hematoma
- Infection at injection site
Key clinical trials
- Analgesic Comparison of Transversus Fascial Plane and Quadratus Lumborum Blocks in Pediatric Urogenital Procedures (NA)
- Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Liver Resection Surgery (NA)
- Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery (NA)
- Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair (NA)
- Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Abendectomy Surgery (NA)
- Comparison of the Effects of Moderate- and High-Dose Glucocorticoids on Postoperative Recovery (NA)
- Postoperative Pain Will be Compared in Cholecystectomy Patients: Half Receiving TAP Block and Half Without it. (NA)
- COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- TAP Block Group CI brief — competitive landscape report
- TAP Block Group updates RSS · CI watch RSS
- Mayo General Hospital, Ireland portfolio CI