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Tablet Pyridoxine hydrochloride
Pyridoxine hydrochloride (vitamin B6) acts as a coenzyme in amino acid metabolism, neurotransmitter synthesis, and hemoglobin formation.
Pyridoxine hydrochloride (vitamin B6) acts as a coenzyme in amino acid metabolism, neurotransmitter synthesis, and hemoglobin formation. Used for Pyridoxine (vitamin B6) deficiency, Nutritional supplementation, Peripheral neuropathy associated with B6 deficiency.
At a glance
| Generic name | Tablet Pyridoxine hydrochloride |
|---|---|
| Also known as | Vitamin B6 |
| Sponsor | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
| Drug class | Vitamin B6 / Essential nutrient |
| Target | Multiple pyridoxal 5-phosphate-dependent enzymes |
| Modality | Small molecule |
| Therapeutic area | Nutritional deficiency / General health |
| Phase | FDA-approved |
Mechanism of action
Pyridoxine is converted to its active form, pyridoxal 5-phosphate, which serves as a cofactor for numerous enzymes involved in protein metabolism, neurotransmitter production (serotonin, dopamine, GABA), and red blood cell formation. It is essential for normal nervous system function, immune response, and homocysteine metabolism.
Approved indications
- Pyridoxine (vitamin B6) deficiency
- Nutritional supplementation
- Peripheral neuropathy associated with B6 deficiency
- Anemia related to B6 deficiency
Common side effects
- Sensory neuropathy (at high doses)
- Nausea
- Headache
Key clinical trials
- Sunitinib or Cediranib for Alveolar Soft Part Sarcoma (PHASE2)
- Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder (PHASE2)
- The Effect of Multiple Micronutrient Supplements in Reducing Anemia in Women of Reproductive Age (NA)
- Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin Under Fed Conditions in Healthy Volunteers (PHASE1)
- Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II (PHASE3)
- Board Game Project for Adolescents with Tourette Syndrome (NA)
- REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment (PHASE4)
- The Effect of Alpha Lipoid Acid and Vitamin B Preparation on Diabetic Polyneuropathy in Type 2 Diabetes Mellitus Patient (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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