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T3 repletion

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Phase 3 active Small molecule

T3 repletion involves the administration of triiodothyronine to replenish the body's stores of this thyroid hormone.

T3 repletion involves the administration of triiodothyronine to replenish the body's stores of this thyroid hormone. Used for Hypothyroidism.

At a glance

Generic nameT3 repletion
Also known asno other name
SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Drug classThyroid hormone
TargetThyroid hormone receptors
ModalitySmall molecule
Therapeutic areaEndocrinology
PhasePhase 3

Mechanism of action

T3 repletion is used to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormones. The goal of T3 repletion is to restore normal thyroid hormone levels in the body, which can help alleviate symptoms such as fatigue, weight gain, and cold intolerance.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results