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Systemic Antibiotic
Systemic antibiotics kill or inhibit the growth of bacteria by targeting essential bacterial structures or metabolic processes.
Systemic antibiotics kill or inhibit the growth of bacteria by targeting essential bacterial structures or metabolic processes. Used for Systemic bacterial infections (specific pathogen and indication not specified).
At a glance
| Generic name | Systemic Antibiotic |
|---|---|
| Also known as | Control arm |
| Sponsor | University Hospital, Geneva |
| Drug class | Antibiotic (class unspecified) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Systemic antibiotics are a broad class of antimicrobial agents that work through various mechanisms depending on the specific antibiotic type—including inhibition of bacterial cell wall synthesis, disruption of protein synthesis, interference with DNA replication, or metabolic pathway inhibition. They are administered orally or parenterally to treat systemic bacterial infections throughout the body.
Approved indications
- Systemic bacterial infections (specific pathogen and indication not specified)
Common side effects
- Gastrointestinal disturbance (nausea, diarrhea, vomiting)
- Allergic reaction
- Photosensitivity
- Hepatotoxicity
- Nephrotoxicity
Key clinical trials
- PMPR and Chlorhexidine on Periodontal Disease and Vascular Function (NA)
- Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity (PHASE2, PHASE3)
- Prophylaxis Against Surgical Site Infections Using Local as Well as Systemic Antibiotic (NA)
- A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation (PHASE2)
- Effects of Treatments on Atopic Dermatitis (PHASE2)
- Evaluation of the Outcome of Fecal Microbiota Transplantation (PHASE1, PHASE2)
- Assessment of Functional Outcomes of Custom-made Articulating Spacers in Two Stage Arthroplasty for Treatment of Infected Hip Joint (NA)
- Study-group on Palliative ERCP And RFA-ablation in Metastatic and Inoperable Pancreatic Tumors (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |