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Symbicort® forte Turbohaler®

University Hospital, Antwerp · FDA-approved active Small molecule

Symbicort combines a long-acting beta-2 agonist (formoterol) and an inhaled corticosteroid (budesonide) to reduce airway inflammation and improve bronchial smooth muscle relaxation.

Symbicort combines a long-acting beta-2 agonist (formoterol) and an inhaled corticosteroid (budesonide) to reduce airway inflammation and improve bronchial smooth muscle relaxation. Used for Asthma maintenance therapy, Chronic obstructive pulmonary disease (COPD) maintenance therapy.

At a glance

Generic nameSymbicort® forte Turbohaler®
SponsorUniversity Hospital, Antwerp
Drug classInhaled corticosteroid/long-acting beta-2 agonist combination (ICS/LABA)
TargetGlucocorticoid receptor (budesonide); beta-2 adrenergic receptor (formoterol)
ModalitySmall molecule
Therapeutic areaRespiratory/Pulmonology
PhaseFDA-approved

Mechanism of action

Budesonide is a corticosteroid that suppresses inflammatory responses in the airways by binding to glucocorticoid receptors, reducing mucus production and airway edema. Formoterol is a long-acting beta-2 agonist that activates beta-2 adrenergic receptors on bronchial smooth muscle, causing bronchodilation and sustained airway opening. The combination provides both anti-inflammatory and bronchodilatory effects for maintenance asthma and COPD control.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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