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Supraclavicular Block
Supraclavicular Block is a Small molecule drug developed by Weill Medical College of Cornell University. It is currently FDA-approved for Anesthesia for upper extremity surgery (shoulder, arm, forearm, hand procedures), Postoperative pain management for upper extremity surgery.
A supraclavicular block is a regional anesthesia technique that interrupts nerve conduction in the upper trunk of the brachial plexus by injecting local anesthetic near the supraclavicular fossa.
A supraclavicular block is a type of regional anesthesia used to manage pain in the upper limb, particularly during surgeries such as elbow surgeries. This block involves the administration of local anesthetics, which can be enhanced by adjuvants like dexmedetomidine, to achieve high-quality analgesia.
At a glance
| Generic name | Supraclavicular Block |
|---|---|
| Sponsor | Weill Medical College of Cornell University |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | FDA-approved |
Mechanism of action
This procedure involves the percutaneous injection of local anesthetic agents (such as lidocaine or bupivacaine) around the upper portion of the brachial plexus as it passes through the supraclavicular region. The anesthetic diffuses into nerve tissue, blocking sodium channels and preventing action potential propagation, thereby producing sensory and motor blockade of the upper extremity. This technique is used to provide anesthesia for surgical procedures on the shoulder, arm, and hand.
Approved indications
- Anesthesia for upper extremity surgery (shoulder, arm, forearm, hand procedures)
- Postoperative pain management for upper extremity surgery
Common side effects
- Horner's syndrome
- Phrenic nerve palsy
- Recurrent laryngeal nerve injury
- Local anesthetic toxicity
- Vascular puncture
- Hematoma
Key clinical trials
- Liposomal Bupivacaine With Standard Bupivacaine Versus Dexmedetomidine With Standard Bupivacaine (PHASE3)
- Evaluation of Supraclavicular Brachial Plexus Blocks at Various Volumes: Impact on Optic Nerve Sheath Diameter (NA)
- Comparative Analgesia and Respiratory Effects of Shoulder Blocks (NA)
- Supraclavicular Block vs Bier's Block for Forearm Trauma Surgery (NA)
- Effect of Adding Dexamethasone to Bupivacaine in Ultrasound-Guided Supraclavicular Brachial Plexus Blocks Versus Bupivacaine Alone for Upper Limb Orthopaedic Surgery
- Supraclavicular Brachial Plexus Block as Opioid Sparing Technique in Pediatrics Undergoing Arteriovenous Fistula Creation (NA)
- Dose-Finding Study: MEV90 for Local Anesthetic in Interscalene Block for Supraclavicular Nerves Block (NA)
- Ropiclobet for Regional Anesthesia and Post-Operative Pain Control in Upper Extremity Surgery (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Supraclavicular Block CI brief — competitive landscape report
- Supraclavicular Block updates RSS · CI watch RSS
- Weill Medical College of Cornell University portfolio CI
Frequently asked questions about Supraclavicular Block
What is Supraclavicular Block?
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Related
- Manufacturer: Weill Medical College of Cornell University — full pipeline
- Therapeutic area: All drugs in Anesthesiology
- Indication: Drugs for Anesthesia for upper extremity surgery (shoulder, arm, forearm, hand procedures)
- Indication: Drugs for Postoperative pain management for upper extremity surgery
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing