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Supplementation of iron sucrose
Supplementation of iron sucrose is a Iron replacement therapy Small molecule drug developed by Medical University of Vienna. It is currently FDA-approved for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients intolerant to or non-responsive to oral iron therapy.
Iron sucrose provides bioavailable iron to replenish depleted iron stores and restore hemoglobin synthesis in patients with iron deficiency anemia.
Iron sucrose provides bioavailable iron to replenish depleted iron stores and restore hemoglobin synthesis in patients with iron deficiency anemia. Used for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients intolerant to or non-responsive to oral iron therapy.
At a glance
| Generic name | Supplementation of iron sucrose |
|---|---|
| Sponsor | Medical University of Vienna |
| Drug class | Iron replacement therapy |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
Mechanism of action
Iron sucrose is a stable complex of iron (III) hydroxide with sucrose that delivers iron intravenously for rapid absorption and utilization by erythroid precursor cells. The iron is incorporated into hemoglobin and myoglobin, restoring oxygen-carrying capacity and correcting anemia. This formulation is particularly useful in patients who cannot tolerate oral iron or require rapid iron repletion, such as those with chronic kidney disease or heavy menstrual bleeding.
Approved indications
- Iron deficiency anemia in patients with chronic kidney disease
- Iron deficiency anemia in patients intolerant to or non-responsive to oral iron therapy
Common side effects
- Hypophosphatemia
- Hyperkalemia
- Injection site reactions
- Headache
- Nausea
- Hypersensitivity reactions
Key clinical trials
- Iron and Immune Response to Vaccine (IRONMUM) (NA)
- Pilot Study Evaluating the Advantages of Sucrosomial® Iron Post-operative Supplementation vs Standard of Care After Cardiac Surgery (EARLY_PHASE1)
- Perioperative Blood Conservation: Role of Combined Iron Supplementation Protocols in Reducing Allogeneic Transfusion (NA)
- The Effect of Combined Iron Protocols on Perioperative Allogeneic Transfusion (NA)
- Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS) (NA)
- Effect of the Combined Programme on Perioperative Anaemia(CPPA) (NA)
- Iron Supplementation for Geriatric Hip Fractures (PHASE4)
- The TARGET-EFT Randomized Clinical Trial (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Supplementation of iron sucrose CI brief — competitive landscape report
- Supplementation of iron sucrose updates RSS · CI watch RSS
- Medical University of Vienna portfolio CI
Frequently asked questions about Supplementation of iron sucrose
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Related
- Drug class: All Iron replacement therapy drugs
- Manufacturer: Medical University of Vienna — full pipeline
- Therapeutic area: All drugs in Hematology
- Indication: Drugs for Iron deficiency anemia in patients with chronic kidney disease
- Indication: Drugs for Iron deficiency anemia in patients intolerant to or non-responsive to oral iron therapy
- Compare: Supplementation of iron sucrose vs similar drugs
- Pricing: Supplementation of iron sucrose cost, discount & access