Last reviewed 2026-04-22 · How we verify

supplementary irrigation

Supplementary irrigation provides additional fluid delivery to maintain hydration and support tissue perfusion during surgical or clinical procedures.

Supplementary irrigation provides additional fluid delivery to maintain hydration and support tissue perfusion during surgical or clinical procedures. Used for Intraoperative fluid management and tissue hydration during surgical procedures.

At a glance

Mechanism of action

Supplementary irrigation refers to the use of additional irrigating solutions (typically saline or balanced electrolyte solutions) administered during surgical procedures to maintain adequate hydration, support hemodynamics, and optimize tissue perfusion. This is a supportive care measure rather than a pharmacologically active drug with a specific molecular mechanism.

Approved indications

• Intraoperative fluid management and tissue hydration during surgical procedures

Common side effects

• Fluid overload
• Electrolyte imbalance
• Hypothermia

Key clinical trials

• The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery (NA)
• Impact of Harvest Lentil Vegetable Blend and Nutrition Education on Turkana Children's Health Outcomes (NA)
• Endoscopic Step-up Approach Vs Aggressive Debridement of Large Pancreatic Walled-off Necrosis (NA)
• A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment (PHASE4)
• COMORAL® the Oral Irrigation Unit Clinical Trial (NA)
• Marine Protein Hydrolysate as Dietary Supplement in Elderly Part II (NA)
• Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques (NA)

Primary sources

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