Last reviewed · How we verify
Sulfentanyl
Sulfentanyl is a Small molecule drug developed by Shenzhen Third People's Hospital. It is currently in Phase 1 development for General anesthesia, Postoperative pain. Also known as: sulfentanil.
Sulfentanyl is a medication that has been studied in clinical trials for various conditions, including sedation and colon cancer, and has been compared to other anesthetics such as etomidate and propofol. The exact mechanism of action of sulfentanyl is not specified in the provided facts, but it is likely related to its opioid receptor activity as indicated by its presence in ChEMBL.
-
Baseline phase 1 → approval rate
+9.6pp
Industry-wide phase 1 drugs reach approval ~9.6% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2033–2036 | — |
| EMA | EU | 2034–2037 | +0.7 yr |
| MHRA | GB | 2034–2037 | +0.7 yr |
| Health Canada | CA | 2034–2038 | +0.9 yr |
| TGA | AU | 2034–2038 | +1.2 yr |
| PMDA | JP | 2034–2038 | +1.5 yr |
| NMPA | CN | 2035–2039 | +2.3 yr |
| MFDS | KR | 2034–2038 | +1.4 yr |
| CDSCO | IN | 2034–2039 | +1.8 yr |
| ANVISA | BR | 2035–2039 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | Sulfentanyl |
|---|---|
| Also known as | sulfentanil |
| Sponsor | Shenzhen Third People's Hospital |
| Target | Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain |
| Phase | Phase 1 |
Approved indications
- General anesthesia
- Postoperative pain
Common side effects
- apnea
- pain
- hypotension
- COVID
- DVT
- bladder spasms
- elevated creatinine
- flu like symptoms
- hypoxemia
- ileus
- intraoperative decrease in compliance
- rash
Key clinical trials
- Effects of Different Drugs for Glottic Atomization on Postoperative Sore Throat After Thyroid Surgery (PHASE4)
- Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (NA)
- Cardiac Index and General Anesthesia Without Opioid. (PHASE2, PHASE3)
- Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology (NA)
- The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
- Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Sulfentanyl CI brief — competitive landscape report
- Sulfentanyl updates RSS · CI watch RSS
- Shenzhen Third People's Hospital portfolio CI
Frequently asked questions about Sulfentanyl
What is Sulfentanyl?
What is Sulfentanyl used for?
Who makes Sulfentanyl?
Is Sulfentanyl also known as anything else?
What development phase is Sulfentanyl in?
What are the side effects of Sulfentanyl?
What does Sulfentanyl target?
Related
- Target: All drugs targeting Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor
- Manufacturer: Shenzhen Third People's Hospital — full pipeline
- Therapeutic area: All drugs in Pain
- Indication: Drugs for General anesthesia
- Indication: Drugs for Postoperative pain
- Also known as: sulfentanil
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing